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    [{"orgOrder":0,"company":"Werewolf Therapeutics","sponsor":"RA Capital Management","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Series B Financing","leadProduct":"WTX-124","moa":"Interleukin-2","graph1":"Oncology","graph2":"Phase I","graph3":"Werewolf Therapeutics","amount2":0.070000000000000007,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0.070000000000000007,"dosageForm":"","sponsorNew":"Werewolf Therapeutics \/ RA Capital Management","highestDevelopmentStatusID":"6","companyTruncated":"Werewolf Therapeutics \/ RA Capital Management"},{"orgOrder":0,"company":"Werewolf Therapeutics","sponsor":"Jefferies","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Public Offering","leadProduct":"WTX-124","moa":"Interleukin-2","graph1":"Oncology","graph2":"Phase I","graph3":"Werewolf 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Applicable"},{"orgOrder":0,"company":"Werewolf Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Gastroenterology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"WTX-921","moa":"","graph1":"Gastroenterology","graph2":"Preclinical","graph3":"Werewolf Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Gastroenterology","amount2New":0,"dosageForm":"","sponsorNew":"Werewolf Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Werewolf Therapeutics \/ Not Applicable"}]

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                            01

                            Werewolf Therapeutics

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                            Lead Product(s) : WTX-921

                            Therapeutic Area : Gastroenterology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Introduces WTX-921, a First-in-Class IL-10 INDUKINE™ for Inflammatory Diseases

                            Details : WTX-921 is a novel IL-10 indukine development candidate for Inflammatory Bowel Disease (IBD) and potentially other inflammatory diseases.

                            Brand Name : WTX-921

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 31, 2024

                            Lead Product(s) : WTX-921

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

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                            Lead Product(s) : WTX-330

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Highlights Data from Phase 1 Trial of WTX-330 for Tumors or Non-Hodgkin Lymphoma

                            Details : WTX-330 is designed to be a systemically dosed prodrug with the ability to deliver fully active IL-12 selectively. Currently, it is being evaluated for the treatment of neoplams.

                            Brand Name : WTX-330

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 25, 2024

                            Lead Product(s) : WTX-330

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : WTX-330

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Therapeutics Announces Initiation of Patient Dosing in Phase 1 Study of WTX-330

                            Details : WTX-330 has the potential to be the only systemic, conditionally active IL-12 therapy with normal tissue IL-12R receptor blockade to deliver the full potency of IL-12 directly to the tumor microenvironment.

                            Brand Name : WTX-330

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 24, 2023

                            Lead Product(s) : WTX-330

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

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                            Lead Product(s) : WTX-330

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Therapeutics Presents Preclinical Data on mWTX-330, a Surrogate IL-12 INDUKINE™ Molecule, at the So...

                            Details : Study data demonstrate that systemic administration of WTX-330, a mouse surrogate INDUKINE molecule, generates potent anti-tumor activity in a cleavage-dependent manner and protective memory against re-challenge in multiple murine syngeneic tumor models.

                            Brand Name : WTX-330

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 10, 2022

                            Lead Product(s) : WTX-330

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

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                            Lead Product(s) : WTX-124,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Therapeutics Announces Initiation of Patient Dosing in Phase 1/1b Clinical Trial of WTX-124 for the T...

                            Details : WTX-124 design consists of wild-type IL-2 cytokine tethered to an inactivation domain to prevent activation in off-target tissue, tumor protease-sensitive linker to allow for activation in tumor micro-environment and half-life extension domain to improve...

                            Brand Name : WTX-124

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 01, 2022

                            Lead Product(s) : WTX-124,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : WTX-124,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Therapeutics Presents Promising Preclinical Data on its Two Lead INDUKINE Molecules at AACR 2022 Annu...

                            Details : WTX-124 and WTX-330 INDUKINE molecules consist of wild-type IL-2 and IL-12 cytokines, tethered to an inactivation domain to prevent activation in peripheral tissue, to allow for activation in tumor microenvironment, and a half-life extension to improve t...

                            Brand Name : WTX-124

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 08, 2022

                            Lead Product(s) : WTX-124,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Merck & Co

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : WTX-613

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Jazz Pharmaceuticals

                            Deal Size : $1,275.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Jazz Pharmaceuticals and Werewolf Therapeutics Announce Exclusive Global License and Collaboration Agreement t...

                            Details : Under the agreement, Jazz has acquired exclusive global development and commercialization rights to Werewolf's investigational WTX-613, a differentiated, conditionally-activated interferon alpha (IFNα) INDUKINE™ molecule in tumors.

                            Brand Name : WTX-613

                            Molecule Type : Large molecule

                            Upfront Cash : $15.0 million

                            April 07, 2022

                            Lead Product(s) : WTX-613

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Jazz Pharmaceuticals

                            Deal Size : $1,275.0 million

                            Deal Type : Licensing Agreement

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                            Lead Product(s) : WTX-124

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Therapeutics Announces Publication of Data Demonstrating the Preclinical Efficacy of WTX-124 in Deliv...

                            Details : Preclinical data show that WTX-124 has an improved therapeutic window compared to recombinant human IL-2 in mouse models and the potential to minimize the toxicity associated with systemic IL-2 administration.

                            Brand Name : WTX-124

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            March 16, 2022

                            Lead Product(s) : WTX-124

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : WTX-124

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Therapeutics to Present Data on its INDUKINE™ Product Candidates at the Society for Immunotherapy o...

                            Details : Company's most advanced product candidates, WTX-124 and WTX-330, are systemically delivered, conditionally activated Interleukin-2 (IL-2) and Interleukin-12 (IL-12) INDUKINE™ molecules, respectively, for the treatment of solid tumors.

                            Brand Name : WTX-124

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 27, 2021

                            Lead Product(s) : WTX-124

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : WTX-124

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Werewolf Therapeutics to Present at Upcoming Next-Gen Cytokine Therapeutics Summit

                            Details : WTX-124 and WTX-330, are systemically delivered, conditionally activated Interleukin-2 (IL-2) and Interleukin-12 (IL-12) INDUKINE molecules, respectively, for the treatment of solid tumors.

                            Brand Name : WTX-124

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 14, 2021

                            Lead Product(s) : WTX-124

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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