[{"orgOrder":0,"company":"Wugen","sponsor":"Alpha Biopharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2021","type":"Partnership","leadProduct":"Memory NK Therapy","moa":"","graph1":"Oncology","graph2":"Phase II","graph3":"Wugen","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"","sponsorNew":"Wugen \/ Alpha Biopharma","highestDevelopmentStatusID":"8","companyTruncated":"Wugen \/ Alpha Biopharma"},{"orgOrder":0,"company":"Wugen","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Cell and Gene therapy","year":"2022","type":"Not Applicable","leadProduct":"WU-CART-007","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Wugen","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous 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Find Clinical Drug Pipeline Developments & Deals by Wugen

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                          Therapeutic Area by Lead Product

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                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : WU-CART-007 is an allogeneic, off-the-shelf, fratricide-resistant CD7-targeted CAR-T cell therapy, engineered to treat relapsed or refractory T cell acute lymphoblastic leukemia or lymphoma.

                          Brand Name : WU-CART-007

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          November 12, 2024

                          Lead Product(s) : WU-CART-007

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Wugen gains non-exclusive clinical and commercial rights to MaxCyte’s Flow Electroporation® technology to support programs like WU-CART-007 for hematologic and solid tumors.

                          Brand Name : WU-CART-007

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          January 30, 2024

                          Lead Product(s) : WU-CART-007

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Recipient : MaxCyte

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : WU-NK-101 is a cytokine-reprogrammed, expanded, cryopreserved, off-the-shelf NK cell product, investigated to treat patients with relapsed or refractory acute myeloid leukemia.

                          Brand Name : WU-NK-101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          August 15, 2023

                          Lead Product(s) : WU-NK-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : WU-CART-007 is an allogeneic, off-the-shelf, fratricide-resistant CD7-targeted CAR-T cell therapy engineered to overcome the technological challenges of harnessing CAR-T cells to treat CD7+ hematological malignancies.

                          Brand Name : WU-CART-007

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 11, 2023

                          Lead Product(s) : Allogeneic CAR-T Cell

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : WU-NK-101 exhibited enhanced metabolic fitness and adaptability, enabling superior resilience within the immunosuppressive solid tumor microenvironment and preserved cytotoxic function.

                          Brand Name : WU-NK-101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 10, 2022

                          Lead Product(s) : WU-NK-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : WU-NK-101’s unique cytokine-induced memory-like phenotype and support its clinical development for solid tumors,including its potent anti-tumor cytotoxicity and enhanced metabolic fitness that supports resilience within immunosuppressive solid TME.

                          Brand Name : WU-NK-101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 04, 2022

                          Lead Product(s) : WU-NK-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : WU-CART-007 is an allogeneic, off-the-shelf, fratricide-resistant CD7-targeted CAR-T cell therapy engineered to overcome the technological challenges of harnessing CAR-T cells to treat CD7+ hematological malignancies.

                          Brand Name : WU-CART-007

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          July 19, 2022

                          Lead Product(s) : WU-CART-007

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The data highlight preclinical activity of WU-NK-101 supporting its clinical development for acute myeloid leukemia (AML). WU-NK-101 displayed activity against AML cell lines both in vitro and in vivo, and improved homing to the bone marrow.

                          Brand Name : WU-NK-101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 12, 2022

                          Lead Product(s) : WU-NK-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : WU-NK-101, novel immunotherapy harnessing the power of memory natural killer (NK) cells to treat liquid and solid tumors, is currently in development for acute myelogenous leukemia (AML) and solid tumors.

                          Brand Name : WU-NK-101

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 24, 2022

                          Lead Product(s) : WU-NK-101

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : WU-CART-007 is an off-the-shelf, fratricide-resistant CD7-targeted CAR-T cell therapy engineered to overcome the technological challenges of harnessing CAR-T cells to treat CD7+ hematological malignancies.

                          Brand Name : WU-CART-007

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 15, 2022

                          Lead Product(s) : WU-CART-007

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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