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Find Clinical Drug Pipeline Developments & Deals by Xalud Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The trial will enroll up to 60 participants in one of two XT-150, a locally-injectable plasmid DNA gene therapy expressing IL-10v, dose groups or placebo for the treatment of facet joint osteoarthritis pain.

                          Brand Name : XT-150

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 02, 2022

                          Lead Product(s) : XT-150

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Fast Track designation is supportive of the clinical significance of our lead candidate, XT-150 that leverages plasmid DNA encoding the anti-inflammatory cytokine IL-10v for the treatment of pain associated with osteoarthritis of the knee.

                          Brand Name : XT-150

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          December 17, 2021

                          Lead Product(s) : XT-150

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The financing positioned Xalud’s to continue advancing lead therapeutic candidate, XT-150, a locally injectable plasmid DNA gene therapy expressing IL-10v – a proprietary long-acting, through clinical development and further expand our platform

                          Brand Name : XT-150

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          August 24, 2021

                          Lead Product(s) : XT-150

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase II

                          Sponsor : PBM Capital

                          Deal Size : $30.0 million

                          Deal Type : Series C Financing

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                          04

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The primary efficacy evaluation of two potential therapeutic doses of XT-150 (150 and 450 μg) will be assessed at six months, followed by an additional six-month safety follow-up with the opportunity for a second injection. Topline results are expected ...

                          Brand Name : XT-150

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          May 20, 2021

                          Lead Product(s) : XT-150

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : XT-150 is currently in a Phase II/III trial for osteoarthritis, and Nguyen expects to read out topline Phase IIb data in Q4. XT-150, is a locally injectable plasmid DNA gene therapy expressing Interleukin 10 (IL-10).

                          Brand Name : XT-150

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          January 22, 2021

                          Lead Product(s) : XT-150

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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