Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : XT-150
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The trial will enroll up to 60 participants in one of two XT-150, a locally-injectable plasmid DNA gene therapy expressing IL-10v, dose groups or placebo for the treatment of facet joint osteoarthritis pain.
Brand Name : XT-150
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
March 02, 2022
Lead Product(s) : XT-150
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : XT-150
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Fast Track designation is supportive of the clinical significance of our lead candidate, XT-150 that leverages plasmid DNA encoding the anti-inflammatory cytokine IL-10v for the treatment of pain associated with osteoarthritis of the knee.
Brand Name : XT-150
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 17, 2021
Lead Product(s) : XT-150
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : XT-150
Therapeutic Area : Musculoskeletal
Study Phase : Phase II
Sponsor : PBM Capital
Deal Size : $30.0 million
Deal Type : Series C Financing
Xalud Therapeutics Completes Oversubscribed $30 Million Series C Financing
Details : The financing positioned Xalud’s to continue advancing lead therapeutic candidate, XT-150, a locally injectable plasmid DNA gene therapy expressing IL-10v – a proprietary long-acting, through clinical development and further expand our platform
Brand Name : XT-150
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 24, 2021
Lead Product(s) : XT-150
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II
Sponsor : PBM Capital
Deal Size : $30.0 million
Deal Type : Series C Financing
Lead Product(s) : XT-150
Therapeutic Area : Musculoskeletal
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The primary efficacy evaluation of two potential therapeutic doses of XT-150 (150 and 450 μg) will be assessed at six months, followed by an additional six-month safety follow-up with the opportunity for a second injection. Topline results are expected ...
Brand Name : XT-150
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
May 20, 2021
Lead Product(s) : XT-150
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : XT-150
Therapeutic Area : Musculoskeletal
Study Phase : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Xalud Therapeutics Appoints Diem Nguyen, Ph.D., as Chief Executive Officer
Details : XT-150 is currently in a Phase II/III trial for osteoarthritis, and Nguyen expects to read out topline Phase IIb data in Q4. XT-150, is a locally injectable plasmid DNA gene therapy expressing Interleukin 10 (IL-10).
Brand Name : XT-150
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
January 22, 2021
Lead Product(s) : XT-150
Therapeutic Area : Musculoskeletal
Highest Development Status : Phase II/ Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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