Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : YOLT-101
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : SHENZHEN SALUBRIS PHARMACEUTICALS
Deal Size : $145.3 million
Deal Type : Licensing Agreement
YolTech Signs Licensing Deal with Salubris For YOLT-101 in China
Details : YolTech will continue to advance the preclinical development of YOLT-101, while Salubris will be responsible for preparing and conducting clinical trials within the licensed territory.
Brand Name : YOLT-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
August 27, 2024
Lead Product(s) : YOLT-101
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : SHENZHEN SALUBRIS PHARMACEUTICALS
Deal Size : $145.3 million
Deal Type : Licensing Agreement
Lead Product(s) : YOLT-203
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
YolTech Administers First Dose of Gene Editing Therapy YOLT-203 for PH1
Details : YOLT-203 is an innovative in vivo gene editing therapy, which is currently being evaluated for the treatment of patients with primary hyperoxaluria type 1 (PH1).
Brand Name : YOLT-203
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
August 22, 2024
Lead Product(s) : YOLT-203
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : YOLT-201
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
First Patient Dosed in Phase I Clinical Trial of YOLT-201
Details : YOLT-201 Injection is a TTR inhibitor oligonucleotide drug candidate. It is being evaluated for the treatment of Transthyretin Amyloidosis Cardiomyopathy.
Brand Name : YOLT-201
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 11, 2024
Lead Product(s) : YOLT-201
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : YOLT-101
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
First Patient Dosed in Clinical Trial of YOLT-101 for the Treatment of FH
Details : YOLT-101, the company's in vivo genome editing candidate being developed as a single dose, potentially curative therapy for the treatment of high-risk heterozygous familial hypercholesterolemia.
Brand Name : YOLT-101
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 02, 2024
Lead Product(s) : YOLT-101
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : YOLT-201
Therapeutic Area : Genetic Disease
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Landmark Clinical Approval for YOLT-201 Obtained by the NMPA
Details : YOLT-201 Injection uses lipid nanoparticles to encapsulate mRNA and sgRNA, forming LNP, and is being evaluated for treating Transthyretin Amyloidosis Cardiomyopathy.
Brand Name : YOLT-201
Molecule Type : Large molecule
Upfront Cash : Not Applicable
March 04, 2024
Lead Product(s) : YOLT-201
Therapeutic Area : Genetic Disease
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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