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Morgan Securities"},{"orgOrder":0,"company":"Zai Lab","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody-drug Conjugate","year":"2025","type":"Inapplicable","leadProduct":"Tisotumab Vedotin","moa":"Tissue factor\/microtubulin","graph1":"Oncology","graph2":"Approved FDF","graph3":"Zai Lab","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Zai Lab \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Zai Lab \/ Inapplicable"}]

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                          01

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                          Details : Tivdak (tisotumab vedotin) is an antibody-drug conjugate that acts as coagulation factor III binding agent & tubulin inhibitor. It is approved for the treatment of cervical cancer.

                          Product Name : Tivdak

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          March 27, 2025

                          Lead Product(s) : Tisotumab Vedotin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          ELCC
                          Not Confirmed
                          ELCC
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                          Details : ZL-1310 is an innovative Antibody-Drug-Conjugate targeting DLL3, it is being developed as a promising therapeutic target in small cell lung cancer and other DLL3+ solid tumors.

                          Product Name : ZL-1310

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          January 22, 2025

                          Lead Product(s) : ZL-1310,Atezolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : KarXT (xanomeline-trospium) is an oral, investigational M1/M4-preferring muscarinic agonist in development for the treatment of psychiatric and neurological conditions, including schizophrenia.

                          Product Name : KarXT

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 17, 2025

                          Lead Product(s) : Xanomeline,Trospium Chloride

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : Tivdak (tisotumab vedotin) is an antibody-drug conjugate that acts as coagulation factor III binding agent & tubulin inhibitor. It is approved for the treatment of cervical cancer.

                          Product Name : Tivdak

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Inapplicable

                          January 15, 2025

                          Lead Product(s) : Tisotumab Vedotin

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved FDF

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : Through the collaboration, Zai Lab will be responsible for all development and commercialization activities in the licensed territory once pove (povetacicept) becomes an approved product.

                          Product Name : Pove

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          January 10, 2025

                          Lead Product(s) : Povetacicept

                          Therapeutic Area : Nephrology

                          Highest Development Status : Phase III

                          Recipient : Vertex Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : Through the collaboration, Zai Lab further expands its oncology pipeline with another potential first-in-class, ADC ZL-6201 targeting multiple solid tumors.

                          Product Name : ZL-6201

                          Product Type : Antibody-drug Conjugate

                          Upfront Cash : Undisclosed

                          January 09, 2025

                          Lead Product(s) : ZL-6201

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : MediLink Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : Tumor Treating Fields therapy concomitantly with gemcitabine and nab-paclitaxel is being investigated as a first-line treatment for unresectable, locally advanced pancreatic adenocarcinoma.

                          Product Name : NovoTTF-200T

                          Product Type : Cytotoxic Drug

                          Upfront Cash : Inapplicable

                          December 02, 2024

                          Lead Product(s) : Gemcitabine,Paclitaxel

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : The collaboration aims for the commercialisation of novel antibacterial drug Xacduro (sulbactam-durlobactam) for the treatment of carbapenem-resistant Acinetobacter baumannii, in mainland China.

                          Product Name : Xacduro

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          November 21, 2024

                          Lead Product(s) : Sulbactam,Durlobactam

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved

                          Sponsor : Pfizer Inc

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          09

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : Vyvgart Hytrulo, a subcutaneous combination of efgartigimod alfa, a human IgG1 antibody fragment and recombinant human hyaluronidase PH20, it is indicated for CIPD.

                          Product Name : Vyvgart Hytrulo

                          Product Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 11, 2024

                          Lead Product(s) : Efgartigimod Alfa,Hyaluronidase

                          Therapeutic Area : Neurology

                          Highest Development Status : Approved

                          Recipient : Argenx

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          ELCC
                          Not Confirmed
                          ELCC
                          Not Confirmed

                          Details : KarXT (xanomeline-trospium) is an oral, investigational M1/M4-preferring muscarinic agonist in development for the treatment of psychiatric and neurological conditions, including schizophrenia.

                          Product Name : KarXT

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 29, 2024

                          Lead Product(s) : Xanomeline,Trospium Chloride

                          Therapeutic Area : Psychiatry/Psychology

                          Highest Development Status : Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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