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Pharma","highestDevelopmentStatusID":"8","companyTruncated":"Kyowa Kirin \/ MEI Pharma"},{"orgOrder":0,"company":"MEI Pharma","sponsor":"Kyowa Kirin","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Zandelisib","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"MEI Pharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"MEI Pharma \/ Kyowa Kirin","highestDevelopmentStatusID":"10","companyTruncated":"MEI Pharma \/ Kyowa Kirin"}]

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                            01

                            MEI Pharma

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                            Lead Product(s) : Zandelisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma and Kyowa Kirin Announce Discontinuation of Zandelisib Development Outside of Japan Following Recen...

                            Details : ME-401 (zandelisib), a selective PI3Kδ inhibitor, is an investigational cancer treatment being developed as an oral, once-daily, treatment for patients with B-cell malignancies.

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 05, 2022

                            Lead Product(s) : Zandelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Kyowa Kirin

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                            Lead Product(s) : Zandelisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Kyowa Kirin and MEI Pharma Announce Topline Data from the Phase 2 MIRAGE Study Evaluating Zandelisib in Patien...

                            Details : ME-401 (zandelisib), a selective PI3Kδ inhibitor, is an investigational cancer treatment being developed as an oral, once-daily, treatment for patients with B-cell malignancies.

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 18, 2022

                            Lead Product(s) : Zandelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : MEI Pharma

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            MEI Pharma

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                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma and Kyowa Kirin Announce Publication in The Lancet Oncology of Data from Phase 1b Clinical Study of...

                            Details : ME-401 (zandelisib), a selective PI3Kδ inhibitor, is an investigational cancer treatment being developed as an oral, once-daily, potential therapeutic option for patients with B-cell malignancies.

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 18, 2022

                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            MEI Pharma

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                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma and Kyowa Kirin Report Clinical Data on Zandelisib at European Hematology Association 2022 Hybrid C...

                            Details : ME-401 (zandelisib), an orally administered investigational phosphatidylinositol 3- kinase delta ("PI3Kδ") inhibitor in clinical development for the treatment of B-cell malignancies

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 10, 2022

                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            MEI Pharma

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                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma and Kyowa Kirin Report New Clinical Data on Zandelisib at American Society of Clinical Oncology Ann...

                            Details : Clinical trials are investigating the efficacy and safety of ME-401 (zandelisib) as a single agent and in combination with other modalities while administered on an Intermittent Dosing Regimen (ID) and in a time-limited manner when dosed in combination.

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 04, 2022

                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            MEI Pharma

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                            Lead Product(s) : Zandelisib

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma and Kyowa Kirin Announce Acceptance of Abstract for Presentation at the American Society of Clinica...

                            Details : ME-401 (Zandelisib), an oral and selective inhibitor of PI3Kδ, is being evaluated in multiple clinical studies, including COASTAL, a Phase 3 study, and TIDAL, a Phase 2 study, in patients with relapsed and refractory follicular and marginal zone lymphom...

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 26, 2022

                            Lead Product(s) : Zandelisib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            MEI Pharma

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                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma and Kyowa Kirin Announce Acceptance of Two Abstracts for Presentation at the European Hematology As...

                            Details : Clinical and preclinical data suggest that ME-401 (zandelisib) distinct characteristics include prolonged target binding, preferential cellular accumulation, high volume of distribution throughout body tissues, and an approx, 28-hour half-life suitable f...

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 12, 2022

                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            MEI Pharma

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                            Lead Product(s) : Zandelisib,Ibrutinib

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma Announces Two Presentations at the American Association for Cancer Research Annual Meeting 2022

                            Details : Data from preclinical studies with ME-401 (zandelisib), a selective PI3Kδ inhibitor, ex vivo in normal human T cells and in vivo in a murine CLL model suggest that zandelisib has immunomodulatory properties on human T cells.

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            April 08, 2022

                            Lead Product(s) : Zandelisib,Ibrutinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            MEI Pharma

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                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma and Kyowa Kirin Provide Regulatory Update on Zandelisib Following Meeting with the FDA

                            Details : ME-401 (zandelisib), a selective phosphatidylinositol-3-kinase inhibitor, an investigational cancer treatment for patients with B-cell malignancies, demonstrated a 70.3% objective response rate in Phase 2 TIDAL study.

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 24, 2022

                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Kyowa Kirin

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            MEI Pharma

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                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            MEI Pharma Announces Acceptance of Two Abstracts for Presentation at the American Association for Cancer Resea...

                            Details : ME-401 (zandelisib), an oral and selective inhibitor of PI3K delta, is being evaluated in multiple clinical studies, including COASTAL and TIDAL study, in patients with follicular and marginal zone lymphomas and other B-cell malignancies.

                            Brand Name : ME-401

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 08, 2022

                            Lead Product(s) : Zandelisib,Rituximab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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