Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Clinical and preclinical data suggest that ME-401 (zandelisib) distinct characteristics include prolonged target binding, preferential cellular accumulation, high volume of distribution throughout body tissues, and an approx, 28-hour half-life suitable f...
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 05, 2022
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : MEI Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ME-401 (zandelisib), a selective PI3Kδ inhibitor, is an investigational cancer treatment being developed as an oral, once-daily, treatment for patients with B-cell malignancies.
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 18, 2022
Lead Product(s) : Zandelisib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : MEI Pharma
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ME-401 (zandelisib), an orally administered investigational phosphatidylinositol 3- kinase delta ("PI3Kδ") inhibitor in clinical development for the treatment of B-cell malignancies
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 06, 2022
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib,Ibrutinib
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Data from preclinical studies with ME-401 (zandelisib), a selective PI3Kδ inhibitor, ex vivo in normal human T cells and in vivo in a murine CLL model suggest that zandelisib has immunomodulatory properties on human T cells.
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 04, 2022
Lead Product(s) : Zandelisib,Ibrutinib
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ME-401 (zandelisib), an oral and selective inhibitor of PI3K delta, is being evaluated in multiple clinical studies, including COASTAL and TIDAL study, in patients with follicular and marginal zone lymphomas and other B-cell malignancies.
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
August 03, 2022
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ME-401 (zandelisib), a selective PI3Kδ inhibitor, is an investigational cancer treatment being developed as an oral, once-daily, potential therapeutic option for patients with B-cell malignancies.
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 18, 2022
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ME-401 (Zandelisib), an oral and selective inhibitor of PI3Kδ, is being evaluated in multiple clinical studies, including COASTAL, a Phase 3 study, and TIDAL, a Phase 2 study, in patients with relapsed and refractory follicular and marginal zone lymphom...
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 26, 2022
Lead Product(s) : Zandelisib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ME-401 (zandelisib), a selective PI3Kδ inhibitor, is an investigational cancer treatment being developed as an oral, once-daily, treatment for patients with B-cell malignancies.
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 12, 2022
Lead Product(s) : Zandelisib
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Clinical trials are investigating the efficacy and safety of ME-401 (zandelisib) as a single agent and in combination with other modalities while administered on an Intermittent Dosing Regimen (ID) and in a time-limited manner when dosed in combination.
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
April 06, 2022
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable
MEI Pharma and Kyowa Kirin Provide Regulatory Update on Zandelisib Following Meeting with the FDA
Details : ME-401 (zandelisib), a selective phosphatidylinositol-3-kinase inhibitor, an investigational cancer treatment for patients with B-cell malignancies, demonstrated a 70.3% objective response rate in Phase 2 TIDAL study.
Product Name : ME-401
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
March 24, 2022
Lead Product(s) : Zandelisib,Rituximab
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Kyowa Kirin
Deal Size : Inapplicable
Deal Type : Inapplicable