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    [{"orgOrder":0,"company":"Nuvalent","sponsor":"J.P. Morgan","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Public Offering","leadProduct":"Zidesamtinib","moa":"ROS1","graph1":"Oncology","graph2":"Phase II","graph3":"Nuvalent","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Nuvalent \/ J.P. Morgan","highestDevelopmentStatusID":"8","companyTruncated":"Nuvalent \/ J.P. Morgan"},{"orgOrder":0,"company":"Nuvalent","sponsor":"J.P. 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Morgan","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Zidesamtinib","moa":"ROS1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Nuvalent","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Nuvalent \/ J.P. Morgan","highestDevelopmentStatusID":"7","companyTruncated":"Nuvalent \/ J.P. Morgan"},{"orgOrder":0,"company":"Nuvalent","sponsor":"J.P. Morgan","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Public Offering","leadProduct":"Zidesamtinib","moa":"ROS1","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Nuvalent","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Nuvalent \/ J.P. Morgan","highestDevelopmentStatusID":"7","companyTruncated":"Nuvalent \/ J.P. Morgan"},{"orgOrder":0,"company":"Nuvalent","sponsor":"J.P. 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    Find Clinical Drug Pipeline Developments & Deals for Zidesamtinib

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                            01

                            Nuvalent

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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $500.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Nuvalent Announces Pricing of Upsized Public Offering of Common Stock

                            Details : The net proceeds will be used to fund the clinical development of NVL-520 (zidesamtinib), which is being evaluated in early-stage clinical studies for the treatment of non-small cell lung cancer.

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            September 16, 2024

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $500.0 million

                            Deal Type : Public Offering

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                            02

                            Nuvalent

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                            Peptide-Based Therapeutics Summit
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                            Peptide-Based Therapeutics Summit
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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Nuvalent Announces Public Offering of Common Stock

                            Details : The net proceeds will be used to fund the clinical development of NVL-520 (zidesamtinib), which is being evaluated in early-stage clinical studies for the treatment of non-small cell lung cancer.

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            September 16, 2024

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : Undisclosed

                            Deal Type : Public Offering

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                            03

                            Nuvalent

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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvalent Receives U.S. FDA Breakthrough Therapy Designation for NVL-520

                            Details : NVL-520 (zidesamtinib) is a novel brain-penetrant ROS1-selective tyrosine kinase inhibitor. It is being evaluated for ROS1-positive metastatic non-small cell lung cancer.

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 27, 2024

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Nuvalent

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                            Peptide-Based Therapeutics Summit
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                            Nuvalent

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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $300.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Nuvalent Announces Pricing of Public Offering of Common Stock

                            Details : The net proceeds will fund clinical development and research of current or additional pipeline candidates including NVL-520, a ROS1-selective tyrosine kinase inhibitor, NVL-655, an ALK-selective inhibitor, and NVL-330, a HER2-selective tyrosine kinase in...

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 16, 2023

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $300.0 million

                            Deal Type : Public Offering

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                            05

                            Nuvalent

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                            Peptide-Based Therapeutics Summit
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                            Nuvalent

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                            Peptide-Based Therapeutics Summit
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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvalent Initiates the Phase 2 Portion of ARROS-1 Clinical Trial for Patients with ROS1-Positive NSCLC and Oth...

                            Details : NVL-520 is a brain-penetrant ROS1-selective inhibitor designed to remain active in tumors that have developed resistance to currently available ROS1 inhibitors, including tumors with the prevalent G2032R resistance mutation and those with the S1986Y/F, L...

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            May 09, 2023

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            Nuvalent

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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvalent Announces Publication in Cancer Discovery Detailing Design and Characterization of ROS1-Selective Inh...

                            Details : NVL-520 is a novel brain-penetrant ROS1-selective inhibitor designed to remain active in tumors that have developed resistance to currently available ROS1 inhibitors, including tumors with the prevalent G2032R resistance mutation.

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            December 13, 2022

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            07

                            Nuvalent

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                            Interphex
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                            Nuvalent

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                            Interphex
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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $230.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Nuvalent Announces Pricing of Public Offering of Common Stock

                            Details : Nuvalent intend to use the net proceeds, to fund research and clinical development of current or additional pipeline candidates including NVL-520, NVL-655 and NVL-330, and for working capital and other general corporate purposes.

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            October 31, 2022

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : J.P. Morgan

                            Deal Size : $230.0 million

                            Deal Type : Public Offering

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                            08

                            Nuvalent

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                            Peptide-Based Therapeutics Summit
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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvalent Reports Preliminary Phase 1 Clinical Data from ARROS-1 Trial that Support Best-In-Class Potential of ...

                            Details : NVL-520 is novel brain-penetrant ROS1-selective inhibitor created with the aim to simultaneously overcome the clinical challenges of emergent treatment resistance, off-target CNS adverse events, and brain metastases that may limit the use of currently av...

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            October 28, 2022

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Nuvalent

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                            Peptide-Based Therapeutics Summit
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                            Nuvalent

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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvalent to Present Preliminary Phase 1 Data from ARROS-1 Clinical Trial of NVL-520 at 34th EORTC-NCI-AACR Sym...

                            Details : NVL-520 is brain-penetrant ROS1-selective inhibitor designed to remain active in tumors that have developed resistance to available ROS1 inhibitors, including tumors with prevalent G2032R resistance mutation and those with S1986Y/F, L2026M, or D2033N res...

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            July 09, 2022

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Nuvalent

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                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Nuvalent Announces Clinical Progress on Parallel Lead Programs NVL-520 and NVL-655 for NSCLC and Solid Tumor C...

                            Details : NVL-520 and NVL-655 have been designed to address the clinical challenges of emergent treatment resistance, off-target CNS adverse events, and brain metastases that may limit the use of currently available ROS1 and ALK kinase inhibitors.

                            Product Name : NVL-520

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            June 21, 2022

                            Lead Product(s) : Zidesamtinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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