11
ALL3
Ra Pharmaceuticals8
UCB Pharma S.AYear
11
ALL1
20243
20233
20221
20213
2020DEALS // DEV.
11
ALL1
Deals10
DevelopmentsCountry
11
ALL8
BELGIUM3
U.S.A11
ALL10
Inapplicable1
UCB Pharma S.ATherapeutic Area
11
ALL10
Immunology1
NeurologyStudy Phase
11
ALL7
Approved FDF2
Phase III1
Phase II1
IND EnablingDeal Type
11
ALL1
Acquisition10
InapplicableProduct Type
11
ALL11
PeptideDosage Form
11
ALL11
Subcutaneous InjectionLead Product
11
ALL11
Zilucoplan SodiumTarget
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ALL11
C5 receptorLead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
ZILBRYSQ® Now Available in The U.S. for Generalized Myasthenia Gravis
Details : Zilbrysq (zilucoplan), the first FDA-approved self-administered C5 complement inhibitor, treats generalized myasthenia gravis in anti-AChR antibody-positive adults.
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
March 01, 2024
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zilbrysq (zilucoplan) is a once-daily, SC, self-administered peptide inhibitor of complement component 5 (C5 inhibitor). As the only once-daily gMG target therapy for self-administration by adult patients with anti-AChR antibody-positive gMG.
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
October 17, 2023
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : RA101495 (zilucoplan) is a once-daily SC, self-administered peptide inhibitor of complement component 5, which is investigated for the treatment of adults with generalized myasthenia gravis.
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
September 15, 2023
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zilbrysq (zilucoplan) is a C5 inhibitor peptide drug candidate, which is currently being evaluated for the treatment of patients with AChR antibody-positive generalized myasthenia gravis.
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
April 12, 2023
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Zilucoplan is a subcutaneous (SC), self-administered peptide inhibitor of complement component 5 (C5 inhibitor) for the treatment of adult patients with acetylcholine receptor antibody positive (AChR-Ab+) generalized myasthenia gravis (gMG).
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
November 14, 2022
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : Phase 3 RAISE and MycarinG studies in generalized myasthenia gravis (gMG) show RA-101495 (zilucoplan) and rozanolixizumab improve gMG-specific outcomes with consistent statistical significance and clinical relevance.
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
October 05, 2022
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
UCB Announces Positive Data in Myasthenia Gravis with Zilucoplan Phase 3 Study Results
Details : The results show zilucoplan was well-tolerated and no major unexpected safety findings were identified compared to earlier zilucoplan studies. The incidence of serious treatment emergent adverse events (TEAEs) in the zilucoplan and placebo treatment arms...
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
April 02, 2022
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
UCB’s Zilucoplan Shows no Relevant Effect in Immune-Mediated Necrotizing Myopathy (IMNM)
Details : The phase 2 study with zilucoplan, a peptide inhibitor of complement component 5 (C5), in immune-mediated necrotizing myopathy (IMNM) did not show a meaningful effect of zilucoplan for people living with IMNM.
Product Name : Zilbrysq
Product Type : Peptide
Upfront Cash : Inapplicable
April 22, 2021
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Ra Pharmaceuticals Announces Publication of Zilucoplan Phase 2 gMG Trial Results in JAMA Neurology
Details : the study demonstrated that zilucoplan resulted in rapid, clinically meaningful, statistically significant, and sustained improvements in the primary and key secondary endpoints.
Product Name : RA101495
Product Type : Peptide
Upfront Cash : Inapplicable
February 18, 2020
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Study Phase : Phase III
Sponsor : UCB Pharma S.A
Deal Size : $2,300.0 million
Deal Type : Acquisition
Details : The transaction will enhance UCB’s potential to be a leader in myasthenia gravis by adding zilucoplan, currently in phase 3, to the UCB pipeline alongside rozanolixizumab.
Product Name : RA101495
Product Type : Peptide
Upfront Cash : Undisclosed
February 04, 2020
Lead Product(s) : Zilucoplan Sodium
Therapeutic Area : Immunology
Highest Development Status : Phase III
Sponsor : UCB Pharma S.A
Deal Size : $2,300.0 million
Deal Type : Acquisition