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III","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Ra Pharmaceuticals \/ UCB Pharma S.A","highestDevelopmentStatusID":"10","companyTruncated":"Ra Pharmaceuticals \/ UCB Pharma S.A"}]

Find Clinical Drug Pipeline Developments & Deals for Zilucoplan

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01

AAN
Not Confirmed
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Details : Zilbrysq (zilucoplan), the first FDA-approved self-administered C5 complement inhibitor, treats generalized myasthenia gravis in anti-AChR antibody-positive adults.

Product Name : Zilbrysq

Product Type : Peptide

Upfront Cash : Inapplicable

March 01, 2024

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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02

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Not Confirmed
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Not Confirmed

Details : Zilbrysq (zilucoplan) is a once-daily, SC, self-administered peptide inhibitor of complement component 5 (C5 inhibitor). As the only once-daily gMG target therapy for self-administration by adult patients with anti-AChR antibody-positive gMG.

Product Name : Zilbrysq

Product Type : Peptide

Upfront Cash : Inapplicable

October 17, 2023

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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03

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Not Confirmed
AAN
Not Confirmed

Details : RA101495 (zilucoplan) is a once-daily SC, self-administered peptide inhibitor of complement component 5, which is investigated for the treatment of adults with generalized myasthenia gravis.

Product Name : Zilbrysq

Product Type : Peptide

Upfront Cash : Inapplicable

September 15, 2023

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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04

AAN
Not Confirmed
AAN
Not Confirmed

Details : Zilbrysq (zilucoplan) is a C5 inhibitor peptide drug candidate, which is currently being evaluated for the treatment of patients with AChR antibody-positive generalized myasthenia gravis.

Product Name : Zilbrysq

Product Type : Peptide

Upfront Cash : Inapplicable

April 12, 2023

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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05

AAN
Not Confirmed
AAN
Not Confirmed

Details : Zilucoplan is a subcutaneous (SC), self-administered peptide inhibitor of complement component 5 (C5 inhibitor) for the treatment of adult patients with acetylcholine receptor antibody positive (AChR-Ab+) generalized myasthenia gravis (gMG).

Product Name : Zilbrysq

Product Type : Peptide

Upfront Cash : Inapplicable

November 14, 2022

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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06

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Not Confirmed
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Not Confirmed

Details : Phase 3 RAISE and MycarinG studies in generalized myasthenia gravis (gMG) show RA-101495 (zilucoplan) and rozanolixizumab improve gMG-specific outcomes with consistent statistical significance and clinical relevance.

Product Name : Zilbrysq

Product Type : Peptide

Upfront Cash : Inapplicable

October 05, 2022

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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07

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Not Confirmed
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Not Confirmed

Details : The results show zilucoplan was well-tolerated and no major unexpected safety findings were identified compared to earlier zilucoplan studies. The incidence of serious treatment emergent adverse events (TEAEs) in the zilucoplan and placebo treatment arms...

Product Name : Zilbrysq

Product Type : Peptide

Upfront Cash : Inapplicable

April 02, 2022

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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08

AAN
Not Confirmed
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Not Confirmed

Details : The phase 2 study with zilucoplan, a peptide inhibitor of complement component 5 (C5), in immune-mediated necrotizing myopathy (IMNM) did not show a meaningful effect of zilucoplan for people living with IMNM.

Product Name : Zilbrysq

Product Type : Peptide

Upfront Cash : Inapplicable

April 22, 2021

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Phase II

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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09

AAN
Not Confirmed
AAN
Not Confirmed

Details : the study demonstrated that zilucoplan resulted in rapid, clinically meaningful, statistically significant, and sustained improvements in the primary and key secondary endpoints.

Product Name : RA101495

Product Type : Peptide

Upfront Cash : Inapplicable

February 18, 2020

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

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10

AAN
Not Confirmed
AAN
Not Confirmed

Details : The transaction will enhance UCB’s potential to be a leader in myasthenia gravis by adding zilucoplan, currently in phase 3, to the UCB pipeline alongside rozanolixizumab.

Product Name : RA101495

Product Type : Peptide

Upfront Cash : Undisclosed

February 04, 2020

Lead Product(s) : Zilucoplan Sodium

Therapeutic Area : Immunology

Highest Development Status : Phase III

Sponsor : UCB Pharma S.A

Deal Size : $2,300.0 million

Deal Type : Acquisition

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