Lead Product(s) : Ziritaxestat
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Gilead Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Galapagos and Gilead Discontinue ISABELA Phase 3 Trials in IPF
Details : The decision is based on the recommendations of the Independent Data Monitoring Committee (IDMC). Patients continued on their standard of care background treatment and were randomized on to either 200 mg or 600 mg ziritaxestat once daily or placebo.
Product Name : GLPG1690
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 02, 2021
Lead Product(s) : Ziritaxestat
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Gilead Sciences
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ziritaxestat
Therapeutic Area : Dermatology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Primary Endpoint Achieved with Ziritaxestat in Novesa Trial in Systemic Sclerosis Patients
Details : Ziritaxestat reached the primary endpoint of the study with a statistically significant change from baseline in the modified Rodnan Skin Score (mRSS) at Week 24, of -8.3 vs -5.7 for placebo.
Product Name : GLPG1690
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 09, 2020
Lead Product(s) : Ziritaxestat
Therapeutic Area : Dermatology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Ziritaxestat
Therapeutic Area : Immunology
Study Phase : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Orphan Drug Designation for GLPG1690 in systemic sclerosis
Details : With the NOVESA Phase 2 trial in SSc fully recruited, the company expects to see topline data in the second half of the year.
Product Name : GLPG1690
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
January 29, 2020
Lead Product(s) : Ziritaxestat
Therapeutic Area : Immunology
Highest Development Status : Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable