Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Zura Submits Tibulizumab Phase 2 Protocol for Systemic Sclerosis to FDA
Details : Tibulizumab, an investigational humanized, tetravalent bispecific dual-antagonist antibody, designed to neutralize both IL-17A and BAFF, for the treatment of systemic sclerosis (SSc) in adults.
Brand Name : ZB-106
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 14, 2024
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Access Biotechnology
Deal Size : $112.5 million
Deal Type : Private Placement
Zura Bio Announces Oversubscribed $112.5 Million Private Placement
Details : Net proceeds will accelerate development of ZB-106 (tibulizumab), including a planned Phase 2 trial in systemic sclerosis and another evaluating its use for hidradenitis suppurativa.
Brand Name : ZB-106
Molecule Type : Large molecule
Upfront Cash : Undisclosed
April 18, 2024
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Access Biotechnology
Deal Size : $112.5 million
Deal Type : Private Placement
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Deep Track Capital
Deal Size : $80.0 million
Deal Type : Private Placement
Details : The funding will allow Zura Bio to initiate a Phase 2 clinical trial for ZB-106 (tibulizumab), a potential first-in-class anti-IL-17 and anti-BAFF dual antagonist, in systemic sclerosis (SSc), followed by a Phase 2 clinical trial in hidradenitis suppurat...
Brand Name : ZB-106
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 06, 2023
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Deep Track Capital
Deal Size : $80.0 million
Deal Type : Private Placement
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Study Phase : Phase I
Recipient : Eli Lilly
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Through the agreement, Zura Bio will expand its Immunology pipeline by including ZB-106 (tibulizumab), a potential first-in-class, anti-IL-17 and anti-BAFF dual antagonist.
Brand Name : ZB-106
Molecule Type : Large molecule
Upfront Cash : $4.2 million
April 27, 2023
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Highest Development Status : Phase I
Recipient : Eli Lilly
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Deep Track Capital
Deal Size : $80.0 million
Deal Type : Private Placement
Details : The net proceedings will be used to to initiate a Phase 2 study for ZB-106 (tibulizumab), a potential first-in-class, anti-IL-17 and anti-BAFF dual antagonist, in Systemic Sclerosis.
Brand Name : ZB-106
Molecule Type : Large molecule
Upfront Cash : $80.0 million
April 27, 2023
Lead Product(s) : Tibulizumab
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Deep Track Capital
Deal Size : $80.0 million
Deal Type : Private Placement
Lead Product(s) : ZB-168
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : JATT Acquisition
Deal Size : Undisclosed
Deal Type : Merger
Zura Bio Limited Announces Closing of Business Combination with JATT Acquisition Corp
Details : The combined company will focus on the clinical development of pipeline candidates ZB-168 and torudokimab. ZB-168 is an anti IL7R α inhibitor that has the potential to impact diseases driven by IL7 and TSLP biological pathways.
Brand Name : ZB-168
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 21, 2023
Lead Product(s) : ZB-168
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : JATT Acquisition
Deal Size : Undisclosed
Deal Type : Merger
Lead Product(s) : ZB-168
Therapeutic Area : Endocrinology
Study Phase : Phase I
Recipient : JATT Acquisition Corp
Deal Size : Undisclosed
Deal Type : Merger
Details : Proceeds from the transaction are expected to provide Zura Bio with the capital needed to accelerate the development of ZB-168, a fully-human, clinical-stage antibody targeting IL7Rα, that was recently in-licensed from Pfizer Inc.
Brand Name : ZB-168
Molecule Type : Large molecule
Upfront Cash : $65.0 million
June 17, 2022
Lead Product(s) : ZB-168
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Recipient : JATT Acquisition Corp
Deal Size : Undisclosed
Deal Type : Merger
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