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Find Clinical Drug Pipeline Developments & Deals by Zura Bio

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                          Top Deals by Deal Size (USD bn)

                          01

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : Tibulizumab, an investigational humanized, tetravalent bispecific dual-antagonist antibody, designed to neutralize both IL-17A and BAFF, for the treatment of systemic sclerosis (SSc) in adults.

                          Brand Name : ZB-106

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 14, 2024

                          Lead Product(s) : Tibulizumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : Net proceeds will accelerate development of ZB-106 (tibulizumab), including a planned Phase 2 trial in systemic sclerosis and another evaluating its use for hidradenitis suppurativa.

                          Brand Name : ZB-106

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          April 18, 2024

                          Lead Product(s) : Tibulizumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Access Biotechnology

                          Deal Size : $112.5 million

                          Deal Type : Private Placement

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                          03

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : The funding will allow Zura Bio to initiate a Phase 2 clinical trial for ZB-106 (tibulizumab), a potential first-in-class anti-IL-17 and anti-BAFF dual antagonist, in systemic sclerosis (SSc), followed by a Phase 2 clinical trial in hidradenitis suppurat...

                          Brand Name : ZB-106

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          June 06, 2023

                          Lead Product(s) : Tibulizumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Deep Track Capital

                          Deal Size : $80.0 million

                          Deal Type : Private Placement

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                          04

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : Through the agreement, Zura Bio will expand its Immunology pipeline by including ZB-106 (tibulizumab), a potential first-in-class, anti-IL-17 and anti-BAFF dual antagonist.

                          Brand Name : ZB-106

                          Molecule Type : Large molecule

                          Upfront Cash : $4.2 million

                          April 27, 2023

                          Lead Product(s) : Tibulizumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Recipient : Eli Lilly

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          05

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : The net proceedings will be used to to initiate a Phase 2 study for ZB-106 (tibulizumab), a potential first-in-class, anti-IL-17 and anti-BAFF dual antagonist, in Systemic Sclerosis.

                          Brand Name : ZB-106

                          Molecule Type : Large molecule

                          Upfront Cash : $80.0 million

                          April 27, 2023

                          Lead Product(s) : Tibulizumab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Deep Track Capital

                          Deal Size : $80.0 million

                          Deal Type : Private Placement

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                          06

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : The combined company will focus on the clinical development of pipeline candidates ZB-168 and torudokimab. ZB-168 is an anti IL7R α inhibitor that has the potential to impact diseases driven by IL7 and TSLP biological pathways.

                          Brand Name : ZB-168

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          March 21, 2023

                          Lead Product(s) : ZB-168

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase I

                          Sponsor : JATT Acquisition

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          07

                          VMX
                          Not Confirmed
                          VMX
                          Not Confirmed

                          Details : Proceeds from the transaction are expected to provide Zura Bio with the capital needed to accelerate the development of ZB-168, a fully-human, clinical-stage antibody targeting IL7Rα, that was recently in-licensed from Pfizer Inc.

                          Brand Name : ZB-168

                          Molecule Type : Large molecule

                          Upfront Cash : $65.0 million

                          June 17, 2022

                          Lead Product(s) : ZB-168

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase I

                          Recipient : JATT Acquisition Corp

                          Deal Size : Undisclosed

                          Deal Type : Merger

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