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Chemistry

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Also known as: 27115-50-0, N-(4-methylbenzoyl)glycine, P-toluric acid, P-methylhippuric acid, N-(p-toluoyl)glycine, Glycine, n-(4-methylbenzoyl)-
Molecular Formula
C10H11NO3
Molecular Weight
193.20  g/mol
InChI Key
NRSCPTLHWVWLLH-UHFFFAOYSA-N
FDA UNII
9QOX0DSK6F

4-Methylhippuric Acid
4-Methylhippuric Acid is an isoform of methylhippuric acid where the methyl and glycine groups are bound to carbon-1 and carbon-4 on the benzene ring, respectively. Since 4-methylhippuric acid (4-MHA) is a metabolite of p-xylene, the measurement of 4-MHA in urine may be correlated to a subject's level of xylene exposure.
1 2D Structure

4-Methylhippuric Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-[(4-methylbenzoyl)amino]acetic acid
2.1.2 InChI
InChI=1S/C10H11NO3/c1-7-2-4-8(5-3-7)10(14)11-6-9(12)13/h2-5H,6H2,1H3,(H,11,14)(H,12,13)
2.1.3 InChI Key
NRSCPTLHWVWLLH-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC=C(C=C1)C(=O)NCC(=O)O
2.2 Other Identifiers
2.2.1 UNII
9QOX0DSK6F
2.3 Synonyms
2.3.1 MeSH Synonyms

1. P-methylhippuric Acid

2. Para-methylhippuric Acid

2.3.2 Depositor-Supplied Synonyms

1. 27115-50-0

2. N-(4-methylbenzoyl)glycine

3. P-toluric Acid

4. P-methylhippuric Acid

5. N-(p-toluoyl)glycine

6. Glycine, N-(4-methylbenzoyl)-

7. 4-methyl Hippuric Acid

8. Hippuric Acid, P-methyl-

9. 2-[(4-methylbenzoyl)amino]acetic Acid

10. 2-(4-methylbenzamido)acetic Acid

11. Para-methylhippuric Acid

12. N-(p-toluoyl)-glycine

13. 9qox0dsk6f

14. 2-[(4-methylphenyl)formamido]acetic Acid

15. Chembl274877

16. Chebi:68552

17. (4-methyl-benzoylamino)-acetic Acid

18. N-[(4-methylphenyl)carbonyl]glycine

19. Nsc-126814

20. ((4-methylbenzoyl)amino)acetic Acid

21. [(4-methylbenzoyl)amino]acetic Acid

22. Unii-9qox0dsk6f

23. N-(p-methylbenzoyl)glycine

24. Nsc 126814

25. P-toluoylglycine

26. Einecs 248-231-8

27. Maybridge1_005796

28. Toluric Acid, P-

29. 4-methylhippuricacid

30. Oprea1_357822

31. 4-methylhippuric Acid, 98%

32. Divk1c_002084

33. Glycine,n-(4-methylbenzoyl)-

34. Schembl1285723

35. 2-(4-methylbenzamido)aceticacid

36. Hms557p10

37. Zinc51120

38. Dtxsid00181580

39. Albb-025852

40. Bbl025689

41. Bdbm50016613

42. Mfcd00020449

43. Nsc126814

44. Stk696186

45. Akos001043926

46. [(4-methylbenzoyl)amino]acetic Acid #

47. Cds1_001044

48. (4-methylbenzoylamino)acetic Acid

49. Cs-0137678

50. Ft-0619087

51. T0313

52. D95330

53. M-3784

54. Sr-01000514107

55. Sr-01000514107-1

56. (((4-methylphenyl)carbonyl)amino)acetic Acid

57. Q22132817

58. Z56899118

59. F1130-0053

2.4 Create Date
2005-03-26
3 Chemical and Physical Properties
Molecular Weight 193.20 g/mol
Molecular Formula C10H11NO3
XLogP31.7
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass193.07389321 g/mol
Monoisotopic Mass193.07389321 g/mol
Topological Polar Surface Area66.4 Ų
Heavy Atom Count14
Formal Charge0
Complexity219
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

4-Methylhippuric Acid Manufacturers

A 4-Methylhippuric Acid manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of 4-Methylhippuric Acid, including repackagers and relabelers. The FDA regulates 4-Methylhippuric Acid manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. 4-Methylhippuric Acid API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

4-Methylhippuric Acid Suppliers

A 4-Methylhippuric Acid supplier is an individual or a company that provides 4-Methylhippuric Acid active pharmaceutical ingredient (API) or 4-Methylhippuric Acid finished formulations upon request. The 4-Methylhippuric Acid suppliers may include 4-Methylhippuric Acid API manufacturers, exporters, distributors and traders.

4-Methylhippuric Acid GMP

4-Methylhippuric Acid Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of 4-Methylhippuric Acid GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right 4-Methylhippuric Acid GMP manufacturer or 4-Methylhippuric Acid GMP API supplier for your needs.

4-Methylhippuric Acid CoA

A 4-Methylhippuric Acid CoA (Certificate of Analysis) is a formal document that attests to 4-Methylhippuric Acid's compliance with 4-Methylhippuric Acid specifications and serves as a tool for batch-level quality control.

4-Methylhippuric Acid CoA mostly includes findings from lab analyses of a specific batch. For each 4-Methylhippuric Acid CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

4-Methylhippuric Acid may be tested according to a variety of international standards, such as European Pharmacopoeia (4-Methylhippuric Acid EP), 4-Methylhippuric Acid JP (Japanese Pharmacopeia) and the US Pharmacopoeia (4-Methylhippuric Acid USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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