Find 4-Tert-Amylphenol manufacturers, exporters & distributors on PharmaCompass

4-Tert-Amylphenol

Gangwal Healthcare is powered by innovation, driving health, wellness & healing.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

$ API Reference Price

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

5 FDF Dossiers, 5 Canada

5 FDF Dossiers
5 Canada

MARKET PLACE

1 APIs

marketPlace
1 APIs

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 1

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 80-46-6, 4-tert-pentylphenol, P-tert-pentylphenol, P-tert-amylphenol, 4-t-amylphenol, 4-(2-methylbutan-2-yl)phenol

Molecular Formula

C₁₁H₁₆O

Molecular Weight

164.24 g/mol

InChI Key

NRZWYNLTFLDQQX-UHFFFAOYSA-N

FDA UNII

6NP9LYK846

tert-amylphenol is a natural product found in Paullinia cupana with data available.

1 2D Structure

4-Tert-Amylphenol

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-(2-methylbutan-2-yl)phenol

2.1.2 InChI

InChI=1S/C11H16O/c1-4-11(2,3)9-5-7-10(12)8-6-9/h5-8,12H,4H2,1-3H3

2.1.3 InChI Key

NRZWYNLTFLDQQX-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCC(C)(C)C1=CC=C(C=C1)O

2.2 Other Identifiers

2.2.1 UNII

6NP9LYK846

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 4-tert-pentyphenol

2. P-tert-amylphenol

3. P-tert-amylphenol, Monopotassium Salt

4. P-tert-amylphenol, Monosodium Salt

5. Para-tertiary-amyl-phenol

2.3.2 Depositor-Supplied Synonyms

1. 80-46-6

2. 4-tert-pentylphenol

3. P-tert-pentylphenol

4. P-tert-amylphenol

5. 4-t-amylphenol

6. 4-(2-methylbutan-2-yl)phenol

7. Pentaphen

8. 4-(1,1-dimethylpropyl)phenol

9. Phenol, 4-(1,1-dimethylpropyl)-

10. Amilphenol

11. Amilfenol

12. Ptap

13. Amyl Phenol 4t

14. Phenol, P-tert-pentyl-

15. Tert-amylphenol

16. P-(1,1-dimethylpropyl)phenol

17. Ucar Amyl Phenol 4t

18. P-t-pentylphenol

19. 4-(tert-pentyl)phenol

20. 2-methyl-2-p-hydroxyphenylbutane

21. 4-(1,1-dimethylpropyl)-1-phenol

22. 1-hydroxy-4-(1,1-dimethylpropyl)benzene

23. 4-t-pentylphenol

24. Phenol, P-(tert-pentyl)-

25. Mfcd00002369

26. Nsc 403672

27. 6np9lyk846

28. Chembl195693

29. Chebi:35096

30. Nsc-403672

31. Ncgc00091655-02

32. P-(.alpha.,.alpha.-dimethylpropyl)phenol

33. Dsstox_cid_1771

34. Phenol,1-dimethylpropyl)-

35. Dsstox_rid_76317

36. Dsstox_gsid_21771

37. Para-tert-amylphenol

38. Caswell No. 050

39. Wln: Qr D1x1&1&1

40. Cas-80-46-6

41. Ccris 4693

42. P-(tert-amyl)phenol

43. Hsdb 5236

44. Einecs 201-280-9

45. P-(alpha,alpha-dimethylpropyl)phenol

46. Epa Pesticide Chemical Code 064101

47. Amylphenol, P-tert-

48. Brn 1908224

49. Unii-6np9lyk846

50. P-tertamylphenol

51. Ai3-00460

52. P-t-amyl Phenol

53. Nipacide Ptap

54. Pentaphen 67

55. Para-tertiary Amylphenol

56. 4-tert-amylphenol, 99%

57. Ec 201-280-9

58. Amylphenol [mart.]

59. Schembl49704

60. 4-06-00-03383 (beilstein Handbook Reference)

61. Mls002152935

62. Bidd:er0210

63. Dtxsid8021771

64. Nrzwynltfldqqx-uhfffaoysa-

65. Nsc4965

66. P-tert-pentylphenol [mi]

67. P-(1,1-dimethyl Propyl) Phenol

68. 4-(1,1-dimethyl-propyl)-phenol

69. Hms3039m10

70. Nsc-4965

71. Zinc1680640

72. Tox21_111159

73. Tox21_202351

74. Tox21_300088

75. Bdbm50410536

76. Nsc403672

77. Akos000119604

78. Tox21_111159_1

79. 4-tert-amylphenol, Analytical Standard

80. 1-hydroxy-4-(2-methyl-2-butyl)benzene

81. Ncgc00091655-01

82. Ncgc00091655-03

83. Ncgc00091655-04

84. Ncgc00091655-05

85. Ncgc00254041-01

86. Ncgc00259900-01

87. Ac-16506

88. Smr001224530

89. Db-000247

90. A0460

91. Am20041188

92. Cs-0152629

93. Ft-0704191

94. 4-(1,1-dimethylpropyl)phenol [hsdb]

95. A24574

96. E76129

97. P-(1,1-dimethylpropyl)phenol;para-tert-amylphenol

98. W-109280

99. Q26840951

100. Z1262246132

2.4 Create Date

2005-03-26

3 Chemical and Physical Properties

Molecular Formula	C₁₁H₁₆O
Molecular Weight	164.24 g/mol
XLogP3	3.9
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	1
Rotatable Bond Count	2
Exact Mass	164.120115130 g/mol
Monoisotopic Mass	164.120115130 g/mol
Topological Polar Surface Area	20.2 Å²
Heavy Atom Count	12
Formal Charge	0
Complexity	132
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Minimum/Potential Fatal Human Dose

3(?). 3 = moderately toxic: probable oral lethal dose (human) 0.5-5 g/kg, between 1 oz and 1 pint for 70 kg person (150 lb).

Gosselin, R.E., R.P. Smith, H.C. Hodge. Clinical Toxicology of Commercial Products. 5th ed. Baltimore: Williams and Wilkins, 1984., p. II-189

5 Pharmacology and Biochemistry

5.1 Absorption, Distribution and Excretion

Assoc of (14)C-labelled p-tert-amylphenol with human serum and bacterial Micrococcus lysodeikticus proteins was most clear-cut among phenolic deriv. Protein binding could explain interference of serum with germicidal effects of phenolic disinfectants.

PMID:5657532 Starr JE et al; J Pharm Sci 57 (5): 768 (1968)

5.2 Metabolism/Metabolites

Yields 4-tert-amylphenyl-beta-d-glucuronide in rabbits; Jellinick, PH, Biochem J, 58, 262 (1954). /From table/

Goodwin, B.L. Handbook of Intermediary Metabolism of Aromatic Compounds. New York: Wiley, 1976., p. A-55

FDF Dossiers