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1. 4-diphenylmethoxy-1-methylpiperidine
2. Diphenylpyraline Hydrochloride
3. Diphenylpyraline Maleate (2:1)
4. Lergobine
1. 147-20-6
2. Hispril
3. Diphenylpyrilene
4. Allergen
5. Diphenylpyralamine
6. Lyssipoll
7. Belfene
8. Dayfen
9. Histryl
10. Histyn
11. Mepiben
12. Neargal
13. 4-(diphenylmethoxy)-1-methylpiperidine
14. 4-(benzhydryloxy)-1-methylpiperidine
15. Difenilpiralina
16. Diphenylpyralinum
17. 1-methyl-4-piperidyl Benzhydryl Ether
18. An 1041
19. 4-benzhydryloxy-1-methylpiperidine
20. Diphenylpyraline (inn)
21. 4-(benzhydryloxy)-n-methylpiperidine
22. Piperidine, 4-(diphenylmethoxy)-1-methyl-
23. Chembl1492
24. 4-diphenylmethoxy-1-methylpiperidine
25. N-methylpiperidyl-(4)-benzhydrylaether Salzsauren Salze
26. P 253
27. 1-methyl-4-hydroxypiperidine Benzhydryl Ether
28. Chebi:59788
29. 33361oe3av
30. 4-benzhydryloxy-1-methyl-piperidine
31. Hystryl
32. Diphenylpyraline [inn]
33. Diphenylpyraline [inn:ban]
34. Difenilpiralina [inn-spanish]
35. Diphenylpyralinum [inn-latin]
36. Nsc61825
37. Ncgc00016395-01
38. Cas-132-18-3
39. Einecs 205-686-7
40. Brn 0245467
41. Unii-33361oe3av
42. N-methylpiperidyl-(4)-benzhydrylaether Salzsauren Salze [german]
43. Diafen (salt/mix)
44. Spectrum_001002
45. 4-[(diphenylmethyl)oxy]-1-methylpiperidine
46. Prestwick0_000707
47. Prestwick1_000707
48. Prestwick2_000707
49. Prestwick3_000707
50. Spectrum2_000982
51. Spectrum3_000401
52. Spectrum4_000521
53. Spectrum5_000917
54. Nciopen2_007716
55. Oprea1_289175
56. Bspbio_000893
57. Bspbio_001922
58. Diphenylpyraline [mi]
59. Kbiogr_001121
60. Kbioss_001482
61. 5-21-01-00053 (beilstein Handbook Reference)
62. Divk1c_000851
63. Schembl119077
64. Spbio_001043
65. Spbio_002814
66. Bpbio1_000983
67. Gtpl7165
68. Diphenylpyraline [vandf]
69. Dtxsid3022952
70. Kbio1_000851
71. Kbio2_001482
72. Kbio2_004050
73. Kbio2_006618
74. Kbio3_001142
75. Zinc56643
76. Diphenylpyraline [who-dd]
77. Ninds_000851
78. Bdbm50241333
79. N-methyl-4-(benzhydryloxy)piperidine
80. Akos015889312
81. Ac-9855
82. Db01146
83. Idi1_000851
84. Ncgc00016395-02
85. Ncgc00016395-03
86. Ncgc00178908-01
87. Ncgc00178908-02
88. 4-(diphenylmethoxy)-1-(methyl)piperidine
89. Sbi-0051354.p003
90. Hy-107431
91. Ab00053461
92. Cs-0028462
93. Ft-0657213
94. D07862
95. Ab00053461_14
96. Ab00053461_15
97. A808623
98. L001180
99. Piperidine, 4-(diphenylmethoxy)-1-methyl
100. Q411150
101. Brd-k22936972-003-05-3
102. Brd-k22936972-003-15-2
Molecular Weight | 281.4 g/mol |
---|---|
Molecular Formula | C19H23NO |
XLogP3 | 3.9 |
Hydrogen Bond Donor Count | 0 |
Hydrogen Bond Acceptor Count | 2 |
Rotatable Bond Count | 4 |
Exact Mass | 281.177964357 g/mol |
Monoisotopic Mass | 281.177964357 g/mol |
Topological Polar Surface Area | 12.5 Ų |
Heavy Atom Count | 21 |
Formal Charge | 0 |
Complexity | 268 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 1 |
For use in the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
Diphenylpyraline is an antihistamine that prevents, but does not reverse, responses mediated by histamine alone. Diphenylpyraline antagonizes most of the pharmacological effects of histamine, including urticaria and pruritus. Also, diphenylpyraline may exhibit anticholinergic actions (as do most of the antihistamines) and may thus provide a drying effect on the nasal mucosa.
R - Respiratory system
R06 - Antihistamines for systemic use
R06A - Antihistamines for systemic use
R06AA - Aminoalkyl ethers
R06AA07 - Diphenylpyraline
Absorption
Well absorbed after oral administration.
Hepatic
Antihistamines such as diphenylpyraline used in the treatment of allergy act by competing with histamine for H1-receptor sites on effector cells. This reduces the effects of histamine, leading to a temporary reduction of allergy symptoms.
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