FRAMINGHAM, Mass., March 22, 2021 /PRNewswire/ -- BERG, a clinical-stage biotech that employs patient biology and artificial intelligence (AI) to research diseases and develop innovative treatments, today announced with leading cancer centers that the Federal Drug Administration [FDA] has authorized a phase 2 trial in glioblastoma multiforme [GBM] patients in neo-adjuvant settings using BERG's BPM 31510. Preclinical evidence in an aggressive orthotopic model of GBM suggests that pre-treatment (priming) followed by co-administration of BPM31510 in combination with standard of care, such as radiation and chemotherapy, led to an increase overall survival rates.
FRAMINGHAM, Mass., Sept. 18, 2020 /PRNewswire/ -- BERG, a clinical-stage biotech that employs artificial intelligence (AI) to investigate diseases and develop innovative treatments, today announced two major medical/clinical research developments on pancreatic ductal adenocarcinoma (PDAC) to be presented virtually at the European Society for Medical Oncology (ESMO) 2020 Congress taking place from September 19-21, 2020.
FRAMINGHAM, Mass., June 1, 2020 /PRNewswire/ -- BERG, a clinical-stage biotech company that uses Artificial Intelligence (AI) to research diseases and develop innovative treatments, today announced results from a Phase 1 clinical study of its investigational drug, BPM 31510 (novel ubidecarenone formulation) in glioblastoma (GBM). The study, presented at the 2020 American Society of Clinical Oncology Annual Meeting (ASCO), highlights safety, tolerability and the impact of BPM 31510-IV influence on metabolism in patients, supporting planned Phase 2 clinical development.