Olatec to Conduct a Phase 2 Trial with its NLRP3 Inhibitor, Dapansutrile
NEW YORK--(BUSINESS WIRE)--Olatec Therapeutics LLC (Olatec) is honored to announce inclusion of their clinical heart failure (HF) study in a recent review manuscript authored by leading researchers and clinicians from Oslo University Hospital, Norway, within the high-impact publication, Journal of the American College of Cardiology (JACC): Basic to Translational Review. Titled “Targeting the Inflammasome in Cardiovascular Disease,” this JACC review demonstrates the cardiology community’s growing confidence in the life-prolonging potential of inhibiting NLRP3 activity to preserve heart function. Moreover, Olatec’s growing body of 1) clinical data in HF patients, which quantified cardiovascular improvements in both ejection fraction and exercise time after a 2-week treatment regimen, and 2) preclinical data in models of heart dysfunction, supports dapansutrile’s therapeutic potential to mitigate the progression of HF and treat its symptoms.
NEW YORK--(BUSINESS WIRE)--Olatec Therapeutics LLC (“Olatec”) today announced the publication of data demonstrating the benefits of its selective NLRP3 inhibitor, dapansutrile, in a mouse model of Alzheimer’s Disease (AD). The data are published in the journal Proceedings of the National Academy of Sciences of the United States of America (PNAS).