OrsoBio to Present Phase 1 and Preclinical Data for Liver-Targeted Mitochondrial Protonophore TLC-6740 at the American Diabetes Association’s 84th Scientific Sessions
OrsoBio, a biotech focused on obesity and metabolic disorders, is getting financial support from one of the leading drugmakers in the field as Eli Lilly helps back its $60 million Series A round.
OrsoBio Announces $60M Series A Financing
OrsoBio to Present Phase 1 Data for Liver-Targeted LXR Inverse Agonist TLC-2716
OrsoBio to Present Phase 1 Data for the Liver-Targeted Mitochondrial Protonophore TLC-6740 in Development for the Treatment of Obesity at ObesityWeek® 2023
PALO ALTO, Calif.--(BUSINESS WIRE)--OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic disorders, today announced completion of the second cohort of subjects in an ongoing Phase 1 trial of TLC-6740, a liver-targeted mitochondrial protonophore. The first-in-human, Phase 1 study is exploring the safety and efficacy of TLC-6740 as an oral, first-in-class, liver-targeted mitochondrial protonophore for the treatment of obesity and obesity-associated diseases, including diabetes and nonalcoholic steatohepatitis (NASH).
OrsoBio Announces First Patient Dosed in Phase 2 Clinical Trial of the ACC2 Inhibitor TLC-3595, a Potential Treatment for Type 2 Diabetes
PALO ALTO, Calif.--(BUSINESS WIRE)--OrsoBio, Inc., a clinical-stage biopharmaceutical company developing treatments for severe metabolic disorders, today announced four development programs that target fundamental pathways of cellular energetics. OrsoBio is led by Chief Executive Officer, Mani Subramanian, MD, PhD, and Chief Medical Officer, Rob Myers, MD, who previously led the Liver Diseases Therapeutic Area at Gilead Sciences. The company was incubated by leading Bay Area-based venture capital firm Samsara BioCapital and builds upon the scientific work of Drs. Gerald Shulman (Yale University), Johan Auwerx (École Polytechnique Fédérale de Lausanne), and Takanori Takebe (Cincinnati Children’s Hospital Medical Center).