Sigachi Industries, a leading player in the pharmaceutical industry, announced the launch of its new product lines, PureCoat and UltraMod - innovative pharmaceutical film coatings and polymer blends, respectively. These cutting-edge solutions are poised to transform the coatings landscape, enhancing drug delivery, patient compliance, and overall product efficacy.
(HiCelTMSMCC) Silicified Microcrystalline Cellulose is made by co-processed technology.HiCelTMSMCC90M grade of Silicified microcrystalline cellulose is used to manufacture the Paracetamol (PCM) tablet using direct compression technology. It is a good choice of excipients for direct compression formulation. The main aim of co-processing is to obtain product with a benefit related to the ratio of it functionality or costing.
Metformin hydrochloride is generally used to regulate blood glucose level; It is mainly used for Insulin- dependent mellitus or Type II diabetes. Type II diabetes mellitus acts by decreasing hepatic glucose output and peripheral insulin resistance. Metformin hydrochloride is a very popular high dose pharmaceutical active. It is normally made by wet granulation method. Wet granulation is more time and man power consuming method. The overall objective of the present work was to develop Metformin hydrochloride tablets prepared by direct compression method, using HiCelTM 90M microcrystalline Cellulose.
Quality of pharmaceutical product is very important because pharmaceuticals drugs should be safe and therapeutically active formulation performance should be consistent and predictable. Final product quality depends on all ingredients which is used for making the final product tablet. Final product tablet is made by the addition of bulk drug and excipients. The continuous evolution of the bulk drugs and excipients can only ensure the quality of final product. Moisture content of API’S and excipients plays a very important role to manufacture the final product. It is may affect the physical and chemical properties of final product. Moisture content affects the physical, chemical and microbiological properties of pharmaceutical finished dosage forms. In direct compression process, high and extra low moisture content could be it affects the hardness of tablet. For satisfactory hardness of tablet, room temperature and humidity must be maintained in a specific limit. Tablet hardness is also most import parameter for any solid dosage form.
The global microcrystalline cellulose (MCC) market is moderately fragmented owing to the presence of a large number of players, states Transparency Market Research in its new study. Key players operating in the global microcrystalline cellulose market are focusing on expansion strategies. Thus, many players are entering into agreements, partnerships, collaborations, and mergers to strengthen their position in the market. Some of the key players operating in the MCC market are Mingtai Chemical Co., Ltd., Asahi Kasei Corporation, J. Rettenmaier & Soehne GmbH + Co KG, Blanver Farmoquimica LTDA, Accent Microcell Pvt. Ltd., FMC Corporation, Juku Orchem Private Limited, DFE Pharma GmbH & Co. KG, Libraw Pharma, Sigachi Industrial Pvt. Ltd., and Avantor Performance Materials, Inc.
Cellulose is the prime component of plant cell. Microcrystalline cellulose is partially depolymerized cellulose, obtained from wood pulp. It is also formed through some of the fungi, bacteria, algae or marine animals. It is insoluble in water and is primarily used as bulking and anticaking agent in production of food products. It is also used as a texturizer, emulsifier and as an extender in application such as pharmaceutical or personal care products. Wide usage of microcrystalline cellulose in manufacturing food products coupled with growing of the pharmaceutical excipient industry is driving the demand of microcrystalline cellulose market across the globe.
The MCC market has witnessed strong growth in the past few years on account of high demand from end use industries in the U.S., Germany, France, China, and India. MCC is gaining importance in the pharmaceutical sector and is growing at a rapid pace. The emphasis of the market players will be on reduction of production cost, which will increase the demand for MCC globally.
The report analyzes and forecasts the market for microcrystalline cellulose on the global and regional level. The market has been forecast based on volume (Tons) and revenue (US$ Thousand) from 2014 to 2020. The study includes drivers and restraints of the global microcrystalline cellulose market. It also covers the impact of these drivers and restraints on demand for microcrystalline cellulose during the forecast period. The report comprises the study of opportunities in the microcrystalline cellulose market on the global and regional level.