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01 1Impurity A; 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one

02 1Impurity A; 2-Propanone, O-(2-methyl-1-oxopropyl) Oxime

03 1Impurity A; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one

04 1Impurity A;3-methyl-Bis-3,7(2-butyn-1-yl)-8-[3-amino-piperidin-1-yl]-xanthine

05 1Impurity B; ((3aR,4R,6R,6aR)-6-(4-(Hydroxyimino)-2-oxo-3,4-dihydropyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl Isobutyrate

06 1Impurity B; (3aR,4R,6R,6aR)-6-(4-Amino-2-oxopyrimidin-1(2H)-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methyl Isobutyrate

07 1Impurity B; 4-amino-1-((3aR,4R,6R,6aR)-6-(hydroxymethyl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)pyrimidin-2(1H)-one sulfate

08 1Impurity B; Diacylated Impurity

09 1Impurity B; Uridine Acylation

10 1Impurity B;1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4(1H,3H)-dione

11 1Impurity B;8-bromo-3-methyl-3,7-dihydro-1H-purine-2,6-dione

12 1Impurity C;8-[(3R)-3-aminopiperidin-1-yl]-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine-2,6-dione

13 1Impurity D; 8-bromo-7-(but-2-yn-1-yl)-3-methyl-3,7-dihydro-1H-purine- 2,6-dione

14 1Impurity E ; 8-bromo-7-(but-2-yn-1-yl)-3-methyl-1-(naphthalen-2-ylmethyl)-3,7-dihydro-1H-purine-2,6-dione

15 1Impurity F;(3R)-1-[(4-methylquinazolin-2-yl) methyl]iperidine-3-amine

16 1Impurity G; 1-[(4-methyl-quinazolin-2yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[-3-hydroxypiperidin-1-yl]-xanthine

17 1Impurity H;1-[(4-methyl-quinazolin-2yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[(R)-3-(tert.-butyoxy carbonylamino)-piperidin-1-yl]-xanthine

18 1Impurity I;1-[(4-methyl-quinazolin-2yl)methyl]-3-methyl-7-(2-butyn-1-yl)-8-[(S)-3-amino-piperidin-1-yl]-xanthine

19 1ImpurityJ;2-(Chloromethyl)-4-methylquinazoline

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