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    Chemistry

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    Also known as: 606-04-2, Pamabrom [usan:usp], Ua8u0kjm72, 606-04-2 (salt), 8-bromotheophylline compound with 2-amino-2-methyl-1-propanol (1:1), 8-bromo-1,3-dimethyl-3,7-dihydro-1h-purine-2,6-dione compound with 2-amino-2-methylpropan-1-ol (1:1)
    Molecular Formula
    C11H18BrN5O3
    Molecular Weight
    348.20  g/mol
    InChI Key
    ATOTUUBRFJHZQG-UHFFFAOYSA-N
    FDA UNII
    UA8U0KJM72
    Pamabrom
    Pamabrom is a mixture containing 2-amino-2-methyl-1-propanol and 8-bromotheophylline (a methylxanthine) in a 1:1 ratio, with mild diuretic activity.
    1 2D Structure

    Pamabrom

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    2-amino-2-methylpropan-1-ol;8-bromo-1,3-dimethyl-7H-purine-2,6-dione
    2.1.2 InChI
    InChI=1S/C7H7BrN4O2.C4H11NO/c1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14;1-4(2,5)3-6/h1-2H3,(H,9,10);6H,3,5H2,1-2H3
    2.1.3 InChI Key
    ATOTUUBRFJHZQG-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC(C)(CO)N.CN1C2=C(C(=O)N(C1=O)C)NC(=N2)Br
    2.2 Other Identifiers
    2.2.1 UNII
    UA8U0KJM72
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. 2-amino-2-methyl-1-propanol-8-bromotheophyllinate

    2. Maximum Strength Aqua-ban

    2.3.2 Depositor-Supplied Synonyms

    1. 606-04-2

    2. Pamabrom [usan:usp]

    3. Ua8u0kjm72

    4. 606-04-2 (salt)

    5. 8-bromotheophylline Compound With 2-amino-2-methyl-1-propanol (1:1)

    6. 8-bromo-1,3-dimethyl-3,7-dihydro-1h-purine-2,6-dione Compound With 2-amino-2-methylpropan-1-ol (1:1)

    7. 2-amino-2-methylpropan-1-ol;8-bromo-1,3-dimethyl-7h-purine-2,6-dione

    8. 8-bromo-3,7-dihydro-1,3-dimethyl-1h-purine-2,6-dione Compound With 2-amino-2-methyl-1-propanol (1:1)

    9. Pamabrom [usan]

    10. 2-amino-2-methylpropanol 8-bromotheophyllinate

    11. Unii-ua8u0kjm72

    12. Backaid

    13. Pamabrom (usp)

    14. Einecs 210-103-4

    15. Pamabrom [mi]

    16. Pamabrom [vandf]

    17. Pamabrom [mart.]

    18. Pamabrom [who-dd]

    19. Schembl92712

    20. Chembl2104825

    21. Pamabrom [usp Monograph]

    22. Dtxsid80209397

    23. Mfcd00867328

    24. S5555

    25. Akos016339632

    26. Ccg-213575

    27. Cs-1106

    28. Db11106

    29. Ks-5228

    30. As-11777

    31. Hy-17391

    32. Db-053667

    33. Ft-0603488

    34. P2359

    35. D08962

    36. T72689

    37. 8-bromotheophylline 2-amino-2-methyl-1-propanol

    38. 606p042

    39. A832802

    40. Q7129023

    41. 8-bromo-1,3-dimethyl-3,9-dihydro-purine-2,6-dione

    42. 2-amino-2-methylpropanol-1-8-bromotheophyllinate

    43. 8-bromo-1,3-dimethyl-1h-purine-2,6(3h,7h)-dione Compound With 2-amino-2-methylpropan-1-ol (1:1)

    2.4 Create Date
    2005-08-08
    3 Chemical and Physical Properties
    Molecular Weight 348.20 g/mol
    Molecular Formula C11H18BrN5O3
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count5
    Rotatable Bond Count1
    Exact Mass347.05930 g/mol
    Monoisotopic Mass347.05930 g/mol
    Topological Polar Surface Area116 Ų
    Heavy Atom Count20
    Formal Charge0
    Complexity340
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2

    API Reference Price

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USP","address":"16\/2,STERLING CENTER,4TH FLOOR,DR.A","city":"MUMBAI ,MAHARASHTRA","supplier":"BAKUL GROUP","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"TO THE ORDER OF","customerCountry":"EGYPT","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"500","totalValueFC":"1388.2","currency":"USD","unitRateINR":38570,"date":"23-May-2024","totalValueINR":"115710","totalValueInUsd":"1388.2","indian_port":"Bombay Air","hs_no":"29395900","bill_no":"1094998","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"16\/2,STERLING CENTER,4TH FLOOR,DR.A, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717093800,"product":"PHARMACEUTICAL RAW MATERIAL\/BULK DRUGS PAMABROM USP","address":"309 HARIKRUPA TOWER NR.OLD-","city":"AHMEDABAD","supplier":"JAI RADHE 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ORDER","customerCountry":"GUATEMALA","quantity":"15.00","actualQuantity":"15","unit":"KGS","unitRateFc":"290","totalValueFC":"4007.3","currency":"USD","unitRateINR":22302,"date":"12-Jun-2024","totalValueINR":"334530","totalValueInUsd":"4007.3","indian_port":"Bombay Air","hs_no":"29395900","bill_no":"1625497","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"GUATEMALA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bombay Air","supplierAddress":"301\/302, ASHFORD CHAMBERS, LADY, MUMBAI, MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725042600,"product":"PAMABROM USP","address":"2 FLR.PRESTIGE PLAZA","city":"AKOTA BARODA","supplier":"AMI LIFESCIENCES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"TO THE ORDER 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STATES","quantity":"1000.00","actualQuantity":"1000","unit":"KGS","unitRateFc":"95","totalValueFC":"94013.7","currency":"USD","unitRateINR":7878.4624999999996,"date":"18-Sep-2024","totalValueINR":"7878462.5","totalValueInUsd":"94013.7","indian_port":"JNPT","hs_no":"29395900","bill_no":"4114512","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED STATES","selfForZScoreResived":"Pharma Grade","supplierPort":"JNPT","supplierAddress":"16\/2,STERLING CENTER,4TH FLOOR,DR.A, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1733423400,"product":"PAMABROM USP","address":"301\/302, ASHFORD CHAMBERS, LADY","city":"MUMBAI, MAHARASHTRA","supplier":"KORES INDIA LIMITED","supplierCountry":"INDIA","foreign_port":"BUSAN(KOREA)","customer":"TO THE ORDER","customerCountry":"REPUBLIC OF 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LIMITED","customerCountry":"PAKISTAN","quantity":"250.00","actualQuantity":"250","unit":"KGS","unitRateFc":"145","totalValueFC":"34862","currency":"USD","unitRateINR":12024.49028,"date":"02-Jan-2025","totalValueINR":"3006122.57","totalValueInUsd":"34862","indian_port":"Ahmedabad Air","hs_no":"29332990","bill_no":"6966069","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"PAKISTAN","selfForZScoreResived":"Pharma Grade","supplierPort":"Ahmedabad Air","supplierAddress":"2 FLR.PRESTIGE PLAZA, AKOTA BARODA","customerAddress":""}]
    22-Feb-2021
    02-Jan-2025
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    ABOUT THIS PAGE

    Looking for 606-04-2 / Pamabrom API manufacturers, exporters & distributors?

    Pamabrom manufacturers, exporters & distributors 1

    45

    PharmaCompass offers a list of Pamabrom API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Pamabrom manufacturer or Pamabrom supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Pamabrom manufacturer or Pamabrom supplier.

    PharmaCompass also assists you with knowing the Pamabrom API Price utilized in the formulation of products. Pamabrom API Price is not always fixed or binding as the Pamabrom Price is obtained through a variety of data sources. The Pamabrom Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Pamabrom

    Synonyms

    606-04-2, Pamabrom [usan:usp], Ua8u0kjm72, 606-04-2 (salt), 8-bromotheophylline compound with 2-amino-2-methyl-1-propanol (1:1), 8-bromo-1,3-dimethyl-3,7-dihydro-1h-purine-2,6-dione compound with 2-amino-2-methylpropan-1-ol (1:1)

    Cas Number

    606-04-2

    Unique Ingredient Identifier (UNII)

    UA8U0KJM72

    About Pamabrom

    Pamabrom is a mixture containing 2-amino-2-methyl-1-propanol and 8-bromotheophylline (a methylxanthine) in a 1:1 ratio, with mild diuretic activity.

    Pamabrom Manufacturers

    A Pamabrom manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Pamabrom, including repackagers and relabelers. The FDA regulates Pamabrom manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Pamabrom API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Pamabrom manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Pamabrom Suppliers

    A Pamabrom supplier is an individual or a company that provides Pamabrom active pharmaceutical ingredient (API) or Pamabrom finished formulations upon request. The Pamabrom suppliers may include Pamabrom API manufacturers, exporters, distributors and traders.

    click here to find a list of Pamabrom suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Pamabrom WC

    A Pamabrom written confirmation (Pamabrom WC) is an official document issued by a regulatory agency to a Pamabrom manufacturer, verifying that the manufacturing facility of a Pamabrom active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Pamabrom APIs or Pamabrom finished pharmaceutical products to another nation, regulatory agencies frequently require a Pamabrom WC (written confirmation) as part of the regulatory process.

    click here to find a list of Pamabrom suppliers with Written Confirmation (WC) on PharmaCompass.

    Pamabrom NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Pamabrom as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Pamabrom API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Pamabrom as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Pamabrom and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Pamabrom NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Pamabrom suppliers with NDC on PharmaCompass.

    Pamabrom GMP

    Pamabrom Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Pamabrom GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Pamabrom GMP manufacturer or Pamabrom GMP API supplier for your needs.

    Pamabrom CoA

    A Pamabrom CoA (Certificate of Analysis) is a formal document that attests to Pamabrom's compliance with Pamabrom specifications and serves as a tool for batch-level quality control.

    Pamabrom CoA mostly includes findings from lab analyses of a specific batch. For each Pamabrom CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Pamabrom may be tested according to a variety of international standards, such as European Pharmacopoeia (Pamabrom EP), Pamabrom JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Pamabrom USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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