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Chemistry

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Also known as: 1180-95-6, Taurodeoxycholate sodium salt, Taurodeoxycholic acid sodium salt, Sodium taurodeoxylate, Taurodeoxycholate (sodium salt), 5pe424s83l
Molecular Formula
C26H44NNaO6S
Molecular Weight
521.7  g/mol
InChI Key
YXHRQQJFKOHLAP-FVCKGWAHSA-M
FDA UNII
5PE424S83L

Taurodeoxycholic Acid
A bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.
1 2D Structure

Taurodeoxycholic Acid

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;2-[[(4R)-4-[(3R,5R,8R,9S,10S,12S,13R,14S,17R)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate
2.1.2 InChI
InChI=1S/C26H45NO6S.Na/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3;/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33);/q;+1/p-1/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-;/m1./s1
2.1.3 InChI Key
YXHRQQJFKOHLAP-FVCKGWAHSA-M
2.1.4 Canonical SMILES
CC(CCC(=O)NCCS(=O)(=O)[O-])C1CCC2C1(C(CC3C2CCC4C3(CCC(C4)O)C)O)C.[Na+]
2.1.5 Isomeric SMILES
C[C@H](CCC(=O)NCCS(=O)(=O)[O-])[C@H]1CC[C@@H]2[C@@]1([C@H](C[C@H]3[C@H]2CC[C@H]4[C@@]3(CC[C@H](C4)O)C)O)C.[Na+]
2.2 Other Identifiers
2.2.1 UNII
5PE424S83L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Acid, Taurodeoxycholic

2. Deoxycholate, Taurine

3. Deoxycholyltaurine

4. Taurine Deoxycholate

5. Taurodeoxycholate

6. Taurodeoxycholate, Sodium

7. Taurodeoxycholic Acid

2.3.2 Depositor-Supplied Synonyms

1. 1180-95-6

2. Taurodeoxycholate Sodium Salt

3. Taurodeoxycholic Acid Sodium Salt

4. Sodium Taurodeoxylate

5. Taurodeoxycholate (sodium Salt)

6. 5pe424s83l

7. Sodium;2-[[(4r)-4-[(3r,5r,8r,9s,10s,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]ethanesulfonate

8. Taurodeoxycholic Acid Sodium Salt Hydrate

9. Sodium 2-((r)-4-((3r,5r,8r,9s,10s,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1h-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate

10. Taurodeoxycholic Acid Sodium

11. Unii-5pe424s83l

12. Mfcd00003671

13. Einecs 214-652-0

14. Akos016009415

15. Cs-w006298

16. Ac-34550

17. Sodium 2-(((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)amino)ethane-1-sulphonate

18. Hy-128853

19. S-6561

20. A836010

21. A893216

22. Q27262693

23. 5beta-cholanic Acid-3alpha,12alpha-diol N-(2-sulphoethyl)-amide Sodium Salt

24. Sodium 2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate

25. Ethanesulfonic Acid, 2-(((3.alpha.,5.beta.,12.alpha.)-3,12-dihydroxy-24-oxocholan-24-yl)amino)-, Monosodium Salt

26. Sodium 2-((4r)-4-((3r,8r,9s,10s,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1h-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate

27. Sodium2-((r)-4-((3r,5r,8r,9s,10s,12s,13r,14s,17r)-3,12-dihydroxy-10,13-dimethylhexadecahydro-1h-cyclopenta[a]phenanthren-17-yl)pentanamido)ethanesulfonate

28. Taurodeoxycholic Acid Sodium Salt; Sodium 2-[[(3a,5b,12a)-3,12-dihydroxy-24-oxocholan-24-yl]amino]ethane-1-sulphonate;taurodeoxycholate Sodium Salt

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 521.7 g/mol
Molecular Formula C26H44NNaO6S
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count7
Exact Mass521.27870358 g/mol
Monoisotopic Mass521.27870358 g/mol
Topological Polar Surface Area135 Ų
Heavy Atom Count35
Formal Charge0
Complexity864
Isotope Atom Count0
Defined Atom Stereocenter Count10
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Cholagogues and Choleretics

Gastrointestinal agents that stimulate the flow of bile into the duodenum (cholagogues) or stimulate the production of bile by the liver (choleretic). (See all compounds classified as Cholagogues and Choleretics.)


Detergents

Purifying or cleansing agents, usually salts of long-chain aliphatic bases or acids, that exert cleansing (oil-dissolving) and antimicrobial effects through a surface action that depends on possessing both hydrophilic and hydrophobic properties. (See all compounds classified as Detergents.)


API Reference Price

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26-Jun-2021
12-Sep-2024
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Looking for 1180-95-6 / Taurodeoxycholic Acid API manufacturers, exporters & distributors?

Taurodeoxycholic Acid manufacturers, exporters & distributors 1

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PharmaCompass also assists you with knowing the Taurodeoxycholic Acid API Price utilized in the formulation of products. Taurodeoxycholic Acid API Price is not always fixed or binding as the Taurodeoxycholic Acid Price is obtained through a variety of data sources. The Taurodeoxycholic Acid Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Taurodeoxycholic Acid

Synonyms

1180-95-6, Taurodeoxycholate sodium salt, Taurodeoxycholic acid sodium salt, Sodium taurodeoxylate, Taurodeoxycholate (sodium salt), 5pe424s83l

Cas Number

1180-95-6

Unique Ingredient Identifier (UNII)

5PE424S83L

About Taurodeoxycholic Acid

A bile salt formed in the liver by conjugation of deoxycholate with taurine, usually as the sodium salt. It is used as a cholagogue and choleretic, also industrially as a fat emulsifier.

Sodium taurodeoxycholate Manufacturers

A Sodium taurodeoxycholate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Sodium taurodeoxycholate, including repackagers and relabelers. The FDA regulates Sodium taurodeoxycholate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Sodium taurodeoxycholate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Sodium taurodeoxycholate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Sodium taurodeoxycholate Suppliers

A Sodium taurodeoxycholate supplier is an individual or a company that provides Sodium taurodeoxycholate active pharmaceutical ingredient (API) or Sodium taurodeoxycholate finished formulations upon request. The Sodium taurodeoxycholate suppliers may include Sodium taurodeoxycholate API manufacturers, exporters, distributors and traders.

click here to find a list of Sodium taurodeoxycholate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Sodium taurodeoxycholate GMP

Sodium taurodeoxycholate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Sodium taurodeoxycholate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Sodium taurodeoxycholate GMP manufacturer or Sodium taurodeoxycholate GMP API supplier for your needs.

Sodium taurodeoxycholate CoA

A Sodium taurodeoxycholate CoA (Certificate of Analysis) is a formal document that attests to Sodium taurodeoxycholate's compliance with Sodium taurodeoxycholate specifications and serves as a tool for batch-level quality control.

Sodium taurodeoxycholate CoA mostly includes findings from lab analyses of a specific batch. For each Sodium taurodeoxycholate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Sodium taurodeoxycholate may be tested according to a variety of international standards, such as European Pharmacopoeia (Sodium taurodeoxycholate EP), Sodium taurodeoxycholate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Sodium taurodeoxycholate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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