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01 1Auro Peptides Limited

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PharmaCompass

01

Cophex
Not Confirmed
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Cophex
Not Confirmed

Linaclotide IH

Date of Issue : 2022-09-07

Valid Till : 2025-06-10

Written Confirmation Number : WC-0443

Address of the Firm : 4th Floor, Survey No. 71 & 72, Indrakaran (V), Kandi (M), Sangareddy (Dist.) Tel...

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Cophex
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Looking for 851199-59-2 / Linaclotide API manufacturers, exporters & distributors?

Linaclotide manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Linaclotide API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Linaclotide manufacturer or Linaclotide supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Linaclotide manufacturer or Linaclotide supplier.

PharmaCompass also assists you with knowing the Linaclotide API Price utilized in the formulation of products. Linaclotide API Price is not always fixed or binding as the Linaclotide Price is obtained through a variety of data sources. The Linaclotide Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Linaclotide

Synonyms

Linzess, 851199-59-2, Chebi:68551, Md-1100, Constella, Cys cys glu tyr cys cys asn pro ala cys thr gly cys tyr (disulfide bridge: 1-6; 2-10; 5-13)

Cas Number

851199-59-2

About Linaclotide

Linaclotide is a synthetic, fourteen amino acid peptide and agonist of intestinal guanylate cyclase type C (GC-C), which is structurally related to the guanylin peptide family, with secretagogue, analgesic and laxative activities. Upon oral administration, linaclotide binds to and activates GC-C receptors located on the luminal surface of the intestinal epithelium. This increases the concentration of intracellular cyclic guanosine monophosphate (cGMP), which is derived from guanosine triphosphate (GTP). cGMP activates the cystic fibrosis transmembrane conductance regulator (CFTR) and stimulates the secretion of chloride and bicarbonate into the intestinal lumen. This promotes sodium excretion into the lumen and results in increased intestinal fluid secretion. This ultimately accelerates GI transit of intestinal contents, improves bowel movement and relieves constipation. Increased extracellular cGMP levels may also exert an antinociceptive effect, through an as of yet not fully elucidated mechanism, that may involve modulation of nociceptors found on colonic afferent pain fibers. Linaclotide is minimally absorbed from the GI tract.

Linzess Manufacturers

A Linzess manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Linzess, including repackagers and relabelers. The FDA regulates Linzess manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Linzess API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Linzess manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Linzess Suppliers

A Linzess supplier is an individual or a company that provides Linzess active pharmaceutical ingredient (API) or Linzess finished formulations upon request. The Linzess suppliers may include Linzess API manufacturers, exporters, distributors and traders.

click here to find a list of Linzess suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Linzess WC

A Linzess written confirmation (Linzess WC) is an official document issued by a regulatory agency to a Linzess manufacturer, verifying that the manufacturing facility of a Linzess active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Linzess APIs or Linzess finished pharmaceutical products to another nation, regulatory agencies frequently require a Linzess WC (written confirmation) as part of the regulatory process.

click here to find a list of Linzess suppliers with Written Confirmation (WC) on PharmaCompass.

Linzess Manufacturers | Traders | Suppliers

Linzess Manufacturers, Traders, Suppliers 1
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We have 2 companies offering Linzess

Get in contact with the supplier of your choice:

  1. Auro Peptides Limited
  2. MSN Laboratories
Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.